49ers’ Backfield Crisis Deepens: Isaac Guerendo Likely Out Against Dolphins Amid Injury Woes

The San Francisco 49ers continue to grapple with a depleted backfield as they prepare to face the Miami Dolphins on Sunday. According to Adam Schefter of ESPN, running back Isaac Guerendo is unlikely to play after sustaining a hamstring injury in last week’s game.

Guerendo, who also dealt with a foot injury from Week 14, has not practiced this week, leaving the 49ers in an even tighter spot at the position.

Guerendo emerged as the team’s lead back following season-ending injuries to Christian McCaffrey and Jordan Mason. In his two starts, Guerendo showcased his versatility, amassing 135 rushing yards and two touchdowns on 31 carries, along with six receptions for 68 yards.

However, his absence would leave the 49ers leaning on Patrick Taylor and Israel Abanikanda, the only two healthy running backs on the active roster. Ke’Shawn Vaughn remains an option from the practice squad as the team looks to adjust to its mounting injuries.